diff --git a/pkgs/build-support/setup-hooks/auto-patchelf.py b/pkgs/build-support/setup-hooks/auto-patchelf.py
index 965384b876fc..261f55854808 100644
--- a/pkgs/build-support/setup-hooks/auto-patchelf.py
+++ b/pkgs/build-support/setup-hooks/auto-patchelf.py
@@ -174,7 +174,7 @@ class Dependency:
     found: bool = False     # Whether it was found somewhere
 
 
-def auto_patchelf_file(path: Path, runtime_deps: list[Path], append_rpaths: List[Path] = []) -> list[Dependency]:
+def auto_patchelf_file(path: Path, runtime_deps: list[Path], append_rpaths: List[Path] = [], extra_args: List[str] = []) -> list[Dependency]:
     try:
         with open_elf(path) as elf:
 
@@ -213,7 +213,7 @@ def auto_patchelf_file(path: Path, runtime_deps: list[Path], append_rpaths: List
     if file_is_dynamic_executable:
         print("setting interpreter of", path)
         subprocess.run(
-                ["patchelf", "--set-interpreter", interpreter_path.as_posix(), path.as_posix()],
+                ["patchelf", "--set-interpreter", interpreter_path.as_posix(), path.as_posix()] + extra_args,
                 check=True)
         rpath += runtime_deps
 
@@ -250,7 +250,7 @@ def auto_patchelf_file(path: Path, runtime_deps: list[Path], append_rpaths: List
     if rpath:
         print("setting RPATH to:", rpath_str)
         subprocess.run(
-                ["patchelf", "--set-rpath", rpath_str, path.as_posix()],
+                ["patchelf", "--set-rpath", rpath_str, path.as_posix()] + extra_args,
                 check=True)
 
     return dependencies
@@ -262,7 +262,8 @@ def auto_patchelf(
         runtime_deps: List[Path],
         recursive: bool = True,
         ignore_missing: List[str] = [],
-        append_rpaths: List[Path] = []) -> None:
+        append_rpaths: List[Path] = [],
+        extra_args: List[str] = []) -> None:
 
     if not paths_to_patch:
         sys.exit("No paths to patch, stopping.")
@@ -275,7 +276,7 @@ def auto_patchelf(
     dependencies = []
     for path in chain.from_iterable(glob(p, '*', recursive) for p in paths_to_patch):
         if not path.is_symlink() and path.is_file():
-            dependencies += auto_patchelf_file(path, runtime_deps, append_rpaths)
+            dependencies += auto_patchelf_file(path, runtime_deps, append_rpaths, extra_args)
 
     missing = [dep for dep in dependencies if not dep.found]
 
@@ -333,6 +334,12 @@ def main() -> None:
         type=Path,
         help="Paths to append to all runtime paths unconditionally",
     )
+    parser.add_argument(
+        "--extra-args",
+        nargs="*",
+        type=str,
+        help="Extra arguments to pass to patchelf"
+    )
 
     print("automatically fixing dependencies for ELF files")
     args = parser.parse_args()
@@ -344,7 +351,8 @@ def main() -> None:
         args.runtime_dependencies,
         args.recursive,
         args.ignore_missing,
-        append_rpaths=args.append_rpaths)
+        append_rpaths=args.append_rpaths,
+        extra_args=args.extra_args)
 
 
 interpreter_path: Path  = None # type: ignore
diff --git a/pkgs/build-support/setup-hooks/auto-patchelf.sh b/pkgs/build-support/setup-hooks/auto-patchelf.sh
index 0625565606f3..371389df427b 100644
--- a/pkgs/build-support/setup-hooks/auto-patchelf.sh
+++ b/pkgs/build-support/setup-hooks/auto-patchelf.sh
@@ -63,6 +63,7 @@ autoPatchelf() {
 
     local appendRunpathsArray=($appendRunpaths)
     local runtimeDependenciesArray=($runtimeDependencies)
+    local patchelfFlagsArray=($patchelfFlags)
     @pythonInterpreter@ @autoPatchelfScript@                            \
         ${norecurse:+--no-recurse}                                      \
         --ignore-missing "${ignoreMissingDepsArray[@]}"                 \
@@ -70,7 +71,8 @@ autoPatchelf() {
         --libs "${autoPatchelfLibs[@]}"                                 \
                "${extraAutoPatchelfLibs[@]}"                            \
         --runtime-dependencies "${runtimeDependenciesArray[@]/%//lib}"  \
-        --append-rpaths "${appendRunpathsArray[@]}"
+        --append-rpaths "${appendRunpathsArray[@]}"                     \
+        --extra-args "${patchelfFlagsArray[@]}"
 }
 
 # XXX: This should ultimately use fixupOutputHooks but we currently don't have