diff --git a/pkgs/development/python-modules/httpretty/setup.py.patch b/pkgs/development/python-modules/httpretty/setup.py.patch
new file mode 100644
index 000000000000..e07ba931705b
--- /dev/null
+++ b/pkgs/development/python-modules/httpretty/setup.py.patch
@@ -0,0 +1,11 @@
+--- setup.py    2016-04-18 10:44:27.915536022 -0500
++++ setup-new.py           2016-04-18 10:44:13.515537377 -0500
+@@ -75,7 +75,7 @@
+
+
+ local_file = lambda *f: \
+-    open(os.path.join(os.path.dirname(__file__), *f)).read()
++    open(os.path.join(os.path.dirname(__file__), *f), encoding="utf-8").read()
+
+
+ install_requires, dependency_links = \
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 92ae7b1eb50d..a32883317ccd 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -10500,7 +10500,6 @@ in modules // {
   httpretty = buildPythonPackage rec {
     name = "httpretty-${version}";
     version = "0.8.6";
-    disabled = isPy3k;
     doCheck = false;
 
     src = pkgs.fetchurl {
@@ -10522,6 +10521,10 @@ in modules // {
       --- 566 ----
       !                 'content-length': str(len(self.body))
       DIFF
+
+      # Explicit encoding flag is required with python3, unless locale is set.
+      ${if !self.isPy3k then "" else
+        "patch -p0 -i ${../development/python-modules/httpretty/setup.py.patch}"}
     '';
 
     meta = {