diff --git a/pkgs/development/guile-modules/guile-gcrypt/default.nix b/pkgs/development/guile-modules/guile-gcrypt/default.nix
index 73152fb9d2c3..7c7e11e3d2b1 100644
--- a/pkgs/development/guile-modules/guile-gcrypt/default.nix
+++ b/pkgs/development/guile-modules/guile-gcrypt/default.nix
@@ -20,11 +20,6 @@ stdenv.mkDerivation rec {
     sha256 = "sha256-lAaiKBOdTFWEWsmwKgx0C67ACvtnEKUxti66dslzSVQ=";
   };
 
-  postConfigure = ''
-    sed -i '/moddir\s*=/s%=.*%=''${out}/share/guile/site%' Makefile;
-    sed -i '/godir\s*=/s%=.*%=''${out}/share/guile/ccache%' Makefile;
-  '';
-
   nativeBuildInputs = [
     autoreconfHook pkg-config texinfo
   ];
@@ -34,6 +29,8 @@ stdenv.mkDerivation rec {
   propagatedBuildInputs = [
     libgcrypt
   ];
+  makeFlags = [ "GUILE_AUTO_COMPILE=0" ];
+  doCheck = true;
 
   meta = with lib; {
     description = "Bindings to Libgcrypt for GNU Guile";
diff --git a/pkgs/development/guile-modules/guile-git/default.nix b/pkgs/development/guile-modules/guile-git/default.nix
index 0b3dfefcbe8c..5487116b53af 100644
--- a/pkgs/development/guile-modules/guile-git/default.nix
+++ b/pkgs/development/guile-modules/guile-git/default.nix
@@ -20,11 +20,6 @@ stdenv.mkDerivation rec {
     sha256 = "x6apF9fmwzrkyzAexKjClOTFrbE31+fVhSLyFZkKRYU=";
   };
 
-  postConfigure = ''
-    sed -i '/moddir\s*=/s%=.*%=''${out}/share/guile/site%' Makefile;
-    sed -i '/godir\s*=/s%=.*%=''${out}/share/guile/ccache%' Makefile;
-  '';
-
   nativeBuildInputs = [
     autoreconfHook pkg-config texinfo
   ];
@@ -34,9 +29,16 @@ stdenv.mkDerivation rec {
   propagatedBuildInputs = [
     libgit2 scheme-bytestructures
   ];
+  doCheck = true;
+  makeFlags = [ "GUILE_AUTO_COMPILE=0" ];
 
   enableParallelBuilding = true;
 
+  # Skipping proxy tests since it requires network access.
+  postConfigure = ''
+    sed -i -e '94i (test-skip 1)' ./tests/proxy.scm
+  '';
+
   meta = with lib; {
     description = "Bindings to Libgit2 for GNU Guile";
     homepage = "https://gitlab.com/guile-git/guile-git";
diff --git a/pkgs/development/guile-modules/guile-json/default.nix b/pkgs/development/guile-modules/guile-json/default.nix
index 1698614c426f..dee81f2baebd 100644
--- a/pkgs/development/guile-modules/guile-json/default.nix
+++ b/pkgs/development/guile-modules/guile-json/default.nix
@@ -15,19 +15,14 @@ stdenv.mkDerivation rec {
     sha256 = "sha256-lCq37FtAhWeZwMqfuBkhrxf8Q2CuvvHMjLH2rZIg1Rk=";
   };
 
-  postConfigure = ''
-    sed -i '/moddir\s*=/s%=.*%=''${out}/share/guile/site%' Makefile;
-    sed -i '/objdir\s*=/s%=.*%=''${out}/share/guile/ccache%' Makefile;
-    sed -i '/moddir\s*=/s%=.*%=''${out}/share/guile/site/json%' json/Makefile;
-    sed -i '/objdir\s*=/s%=.*%=''${out}/share/guile/ccache/json%' json/Makefile;
-  '';
-
   nativeBuildInputs = [
     pkg-config texinfo
   ];
   buildInputs = [
     guile
   ];
+  doCheck = true;
+  makeFlags = [ "GUILE_AUTO_COMPILE=0" ];
 
   meta = with lib; {
     description = "JSON Bindings for GNU Guile";
diff --git a/pkgs/development/scheme-modules/scheme-bytestructures/default.nix b/pkgs/development/scheme-modules/scheme-bytestructures/default.nix
index 602b0d86f44b..1cbbdf0bf29d 100644
--- a/pkgs/development/scheme-modules/scheme-bytestructures/default.nix
+++ b/pkgs/development/scheme-modules/scheme-bytestructures/default.nix
@@ -17,11 +17,6 @@ stdenv.mkDerivation rec {
     sha256 = "sha256-Wvs288K8BVjUuWvvzpDGBwOxL7mAXjVtgIwJAsQd0L4=";
   };
 
-  postConfigure = ''
-    sed -i '/moddir\s*=/s%=.*%=''${out}/share/guile/site%' Makefile;
-    sed -i '/godir\s*=/s%=.*%=''${out}/share/guile/ccache%' Makefile;
-  '';
-
   nativeBuildInputs = [
     autoreconfHook pkg-config
   ];
@@ -29,6 +24,9 @@ stdenv.mkDerivation rec {
     guile
   ];
 
+  doCheck = true;
+  makeFlags = [ "GUILE_AUTO_COMPILE=0" ];
+
   meta = with lib; {
     description = "Structured access to bytevector contents";
     homepage = "https://github.com/TaylanUB/scheme-bytestructures";