diff --git a/pkgs/development/python2-modules/pillow/default.nix b/pkgs/development/python2-modules/pillow/default.nix
deleted file mode 100644
index 61242c894a89..000000000000
--- a/pkgs/development/python2-modules/pillow/default.nix
+++ /dev/null
@@ -1,47 +0,0 @@
-{ lib, stdenv, buildPythonPackage, fetchPypi, isPyPy, isPy3k
-, olefile, freetype, libjpeg, zlib, libtiff, libwebp, tcl, lcms2, tk, libX11
-, openjpeg, libimagequant, pyroma, numpy, pytestCheckHook
-}@args:
-
-import ./generic.nix (rec {
-  pname = "Pillow";
-  version = "6.2.2";
-
-  disabled = !isPy3k;
-
-  src = fetchPypi {
-    inherit pname version;
-    sha256 = "0l5rv8jkdrb5q846v60v03mcq64yrhklidjkgwv6s1pda71g17yv";
-  };
-
-  meta = with lib; {
-    homepage = "https://python-pillow.org/";
-    description = "The friendly PIL fork (Python Imaging Library)";
-    longDescription = ''
-      The Python Imaging Library (PIL) adds image processing
-      capabilities to your Python interpreter.  This library
-      supports many file formats, and provides powerful image
-      processing and graphics capabilities.
-    '';
-    license = "http://www.pythonware.com/products/pil/license.htm";
-    maintainers = with maintainers; [ goibhniu prikhi SuperSandro2000 ];
-    knownVulnerabilities = [
-      "CVE-2020-10177"
-      "CVE-2020-10378"
-      "CVE-2020-10379"
-      "CVE-2020-10994"
-      "CVE-2020-11538"
-      "CVE-2020-35653"
-      "CVE-2020-35654"
-      "CVE-2020-35655"
-      "CVE-2021-25289"
-      "CVE-2021-25290"
-      "CVE-2021-25291"
-      "CVE-2021-25292"
-      "CVE-2021-25293"
-      "CVE-2021-27921"
-      "CVE-2021-27922"
-      "CVE-2021-27923"
-    ];
-  };
-} // args )
diff --git a/pkgs/development/python2-modules/pillow/generic.nix b/pkgs/development/python2-modules/pillow/generic.nix
deleted file mode 100644
index 3e33f1a8aa0f..000000000000
--- a/pkgs/development/python2-modules/pillow/generic.nix
+++ /dev/null
@@ -1,77 +0,0 @@
-{ pname
-, version
-, disabled
-, src
-, meta
-, ...
-}@args:
-
-with args;
-
-buildPythonPackage rec {
-  inherit pname version src meta;
-
-  # Disable imagefont tests, because they don't work well with infinality:
-  # https://github.com/python-pillow/Pillow/issues/1259
-  postPatch = ''
-    rm Tests/test_imagefont.py
-  '';
-
-  # Disable darwin tests which require executables: `iconutil` and `screencapture`
-  disabledTests = lib.optionals stdenv.isDarwin [
-    "test_grab"
-    "test_grabclipboard"
-    "test_save"
-
-    # pillow-simd
-    "test_roundtrip"
-    "test_basic"
-  ] ++ lib.optionals (lib.versions.major version == "6") [
-    # RuntimeError: Error setting from dictionary
-    "test_custom_metadata"
-  ];
-
-  propagatedBuildInputs = [ olefile ]
-    ++ lib.optionals (lib.versionAtLeast version "8.2.0") [ defusedxml ];
-
-  checkInputs = [ pytestCheckHook pyroma numpy ];
-
-  buildInputs = [ freetype libjpeg openjpeg libimagequant zlib libtiff libwebp tcl lcms2 ]
-    ++ lib.optionals (lib.versionAtLeast version "7.1.0") [ libxcb ]
-    ++ lib.optionals (isPyPy) [ tk libX11 ];
-
-  # NOTE: we use LCMS_ROOT as WEBP root since there is not other setting for webp.
-  # NOTE: The Pillow install script will, by default, add paths like /usr/lib
-  # and /usr/include to the search paths. This can break things when building
-  # on a non-NixOS system that has some libraries installed that are not
-  # installed in Nix (for example, Arch Linux has jpeg2000 but Nix doesn't
-  # build Pillow with this support). We patch the `disable_platform_guessing`
-  # setting here, instead of passing the `--disable-platform-guessing`
-  # command-line option, since the command-line option doesn't work when we run
-  # tests.
-  preConfigure = let
-    libinclude' = pkg: ''"${pkg.out}/lib", "${pkg.out}/include"'';
-    libinclude = pkg: ''"${pkg.out}/lib", "${pkg.dev}/include"'';
-  in ''
-    sed -i "setup.py" \
-        -e 's|^FREETYPE_ROOT =.*$|FREETYPE_ROOT = ${libinclude freetype}|g ;
-            s|^JPEG_ROOT =.*$|JPEG_ROOT = ${libinclude libjpeg}|g ;
-            s|^JPEG2K_ROOT =.*$|JPEG2K_ROOT = ${libinclude openjpeg}|g ;
-            s|^IMAGEQUANT_ROOT =.*$|IMAGEQUANT_ROOT = ${libinclude' libimagequant}|g ;
-            s|^ZLIB_ROOT =.*$|ZLIB_ROOT = ${libinclude zlib}|g ;
-            s|^LCMS_ROOT =.*$|LCMS_ROOT = ${libinclude lcms2}|g ;
-            s|^TIFF_ROOT =.*$|TIFF_ROOT = ${libinclude libtiff}|g ;
-            s|^TCL_ROOT=.*$|TCL_ROOT = ${libinclude' tcl}|g ;
-            s|self\.disable_platform_guessing = None|self.disable_platform_guessing = True|g ;'
-    export LDFLAGS="$LDFLAGS -L${libwebp}/lib"
-    export CFLAGS="$CFLAGS -I${libwebp}/include"
-  '' + lib.optionalString (lib.versionAtLeast version "7.1.0") ''
-    export LDFLAGS="$LDFLAGS -L${libxcb}/lib"
-    export CFLAGS="$CFLAGS -I${libxcb.dev}/include"
-  '' + lib.optionalString stdenv.isDarwin ''
-    # Remove impurities
-    substituteInPlace setup.py \
-      --replace '"/Library/Frameworks",' "" \
-      --replace '"/System/Library/Frameworks"' ""
-  '';
-}
diff --git a/pkgs/top-level/python2-packages.nix b/pkgs/top-level/python2-packages.nix
index 5964562c3ad0..460eabd1053a 100644
--- a/pkgs/top-level/python2-packages.nix
+++ b/pkgs/top-level/python2-packages.nix
@@ -57,11 +57,6 @@ with self; with super; {
 
   packaging = callPackage ../development/python2-modules/packaging { };
 
-  pillow = callPackage ../development/python2-modules/pillow {
-    inherit (pkgs) freetype libjpeg zlib libtiff libwebp tcl lcms2 tk;
-    inherit (pkgs.xorg) libX11;
-  };
-
   pip = callPackage ../development/python2-modules/pip { };
 
   pluggy = callPackage ../development/python2-modules/pluggy { };