diff --git a/pkgs/development/python-modules/pyxb/default.nix b/pkgs/development/python-modules/pyxb/default.nix
deleted file mode 100644
index de4c4e8b9689..000000000000
--- a/pkgs/development/python-modules/pyxb/default.nix
+++ /dev/null
@@ -1,30 +0,0 @@
-{ lib
-, buildPythonPackage
-, fetchPypi
-}:
-
-buildPythonPackage rec {
-  pname = "PyXB";
-  version = "1.2.6";
-  format = "setuptools";
-
-  src = fetchPypi {
-    inherit pname version;
-    sha256 = "1d17pyixbfvjyi2lb0cfp0ch8wwdf44mmg3r5pwqhyyqs66z601a";
-  };
-
-  pythonImportsCheck = [
-    "pyxb"
-  ];
-
-  # tests don't complete
-  # https://github.com/pabigot/pyxb/issues/130
-  doCheck = false;
-
-  meta = with lib; {
-    description = "Python XML Schema Bindings";
-    homepage = "https://github.com/pabigot/pyxb";
-    license = licenses.asl20;
-    maintainers = with maintainers; [ hexa ];
-  };
-}
diff --git a/pkgs/top-level/python-aliases.nix b/pkgs/top-level/python-aliases.nix
index 31174bfa1f1a..0045e92c5385 100644
--- a/pkgs/top-level/python-aliases.nix
+++ b/pkgs/top-level/python-aliases.nix
@@ -386,6 +386,7 @@ mapAliases ({
   pyvcf = throw "pyvcf has been removed, it was using setuptools 2to3 translation feature, which has been removed in setuptools 58"; # added 2023-05-19
   PyVirtualDisplay = pyvirtualdisplay; # added 2023-02-19
   pywick = throw "pywick has been removed, since it is no longer maintained"; # added 2023-07-01
+  pyxb = throw "pyxb has been removed, its last release was in 2017 and it has finally been archived in April 2023."; # added 2024-01-05
   qasm2image = throw "qasm2image is no longer maintained (since November 2018), and is not compatible with the latest pythonPackages.qiskit versions."; # added 2020-12-09
   qds_sdk = qds-sdk; # added 2023-10-21
   Quandl = quandl; # added 2023-02-19
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 251b24fa315a..d087b548ef3e 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -12118,8 +12118,6 @@ self: super: with self; {
 
   pyx = callPackage ../development/python-modules/pyx { };
 
-  pyxb = callPackage ../development/python-modules/pyxb { };
-
   pyxbe = callPackage ../development/python-modules/pyxbe { };
 
   pyxdg = callPackage ../development/python-modules/pyxdg { };