diff --git a/pkgs/applications/networking/remote/freerdp/default.nix b/pkgs/applications/networking/remote/freerdp/default.nix
index 89e952945c87..ea09e1a942f1 100644
--- a/pkgs/applications/networking/remote/freerdp/default.nix
+++ b/pkgs/applications/networking/remote/freerdp/default.nix
@@ -37,6 +37,11 @@
 , libjpeg_turbo
 , buildServer ? true
 , nocaps ? false
+, AudioToolbox
+, AVFoundation
+, Carbon
+, Cocoa
+, CoreMedia
 }:
 
 let
@@ -47,6 +52,11 @@ let
       dir = "libfreerdp/crypto/test";
       file = "Test_x509_cert_info.c";
     }
+  ] ++ lib.optionals stdenv.isDarwin [
+    {
+      dir = "winpr/libwinpr/sysinfo/test";
+      file = "TestGetComputerName.c";
+    }
   ];
 
 in
@@ -64,6 +74,9 @@ stdenv.mkDerivation rec {
   postPatch = ''
     export HOME=$TMP
 
+    # skip NIB file generation on darwin
+    sed -z 's/NIB file generation.*//' -i client/Mac{,/cli}/CMakeLists.txt
+
     # failing test(s)
     ${lib.concatMapStringsSep "\n" (e: ''
       substituteInPlace ${e.dir}/CMakeLists.txt \
@@ -82,7 +95,6 @@ stdenv.mkDerivation rec {
   '';
 
   buildInputs = [
-    alsa-lib
     cairo
     cups
     ffmpeg
@@ -111,9 +123,18 @@ stdenv.mkDerivation rec {
     orc
     pcre
     pcsclite
-    wayland
     zlib
-  ] ++ lib.optional stdenv.isLinux systemd;
+  ] ++ lib.optionals stdenv.isLinux [
+    alsa-lib
+    systemd
+    wayland
+  ] ++ lib.optionals stdenv.isDarwin [
+    AudioToolbox
+    AVFoundation
+    Carbon
+    Cocoa
+    CoreMedia
+  ];
 
   nativeBuildInputs = [ cmake pkg-config ];
 
@@ -132,8 +153,19 @@ stdenv.mkDerivation rec {
     WITH_VAAPI = true;
     WITH_JPEG = (libjpeg_turbo != null);
     WITH_CAIRO = (cairo != null);
+    WITH_X11 = true;
   };
 
+  NIX_CFLAGS_COMPILE = lib.optional stdenv.isDarwin [
+    "-DTARGET_OS_IPHONE=0"
+    "-DTARGET_OS_WATCH=0"
+    "-include AudioToolbox/AudioToolbox.h"
+  ];
+
+  NIX_LDFLAGS = lib.optionals stdenv.isDarwin [
+    "-framework AudioToolbox"
+  ];
+
   meta = with lib; {
     description = "A Remote Desktop Protocol Client";
     longDescription = ''
diff --git a/pkgs/development/libraries/gtk-frdp/default.nix b/pkgs/development/libraries/gtk-frdp/default.nix
index 4498930bd838..a76805d8d1fb 100644
--- a/pkgs/development/libraries/gtk-frdp/default.nix
+++ b/pkgs/development/libraries/gtk-frdp/default.nix
@@ -44,6 +44,11 @@ stdenv.mkDerivation rec {
     };
   };
 
+  NIX_CFLAGS_COMPILE = lib.optional stdenv.isDarwin [
+    "-DTARGET_OS_IPHONE=0"
+    "-DTARGET_OS_WATCH=0"
+  ];
+
   meta = with lib; {
     homepage = "https://gitlab.gnome.org/GNOME/gtk-frdp";
     description = "RDP viewer widget for GTK";
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index b4335a67d37c..5bbd7b64d18b 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -28436,6 +28436,7 @@ with pkgs;
   xrdp = callPackage ../applications/networking/remote/xrdp { };
 
   freerdp = callPackage ../applications/networking/remote/freerdp {
+    inherit (darwin.apple_sdk.frameworks) AudioToolbox AVFoundation Carbon Cocoa CoreMedia;
     inherit (gst_all_1) gstreamer gst-plugins-base gst-plugins-good;
   };